DCCP and DICP: Construction and Analyses of Databases for Copper- and Iron-Chelating Proteins
نویسندگان
چکیده
Copper and iron play important roles in a variety of biological processes, especially when being chelated with proteins. The proteins involved in the metal binding, transporting and metabolism have aroused much interest. To facilitate the study on this topic, we constructed two databases (DCCP and DICP) containing the known copper- and iron-chelating proteins, which are freely available from the website http://sdbi.sdut.edu.cn/en. Users can conveniently search and browse all of the entries in the databases. Based on the two databases, bioinformatic analyses were performed, which provided some novel insights into metalloproteins.
منابع مشابه
Processing Time Effects on Functional and Antioxidant Properties of the Quinoa Proteins Hydrolyzed with Alcalase and Pancreatin
Background and Objectives: Antioxidants are used to decrease oxidation of oils and increase shelf life of foods for centuries. Nowadays, researchers investigate for the replacement of synthetic antioxidants with antioxidants from natural sources. The purpose of this study was to investigate effects of quinoa enzyme-hydrolyzed proteins on functional and antioxidant properties of the produced pep...
متن کاملThe Stabilising and Chelating Effects of Green and Roasted Coffee Extracts
ABSTRACT: Oxidation might be regarded as one of the most important reaction in oils and fats. Prooxidants namely iron and copper intensify and catalyze the oxidation while the chelating agents might retard or delay this process. Citric acid, phosphoric acid, some of phenolic compounds and phospholipids are considered as the compounds that chelate the prooxidant metals and through this mechanism...
متن کاملZolqarnein’s Dam Construction
The Holy Quran is God’s miracle and its scientific miracle aspects or wonders have been recognized by development of human scientific abilities. Stating the story of Zolqarnein and dam construction by him, verses 83 to 98 of Al-Kahf have pointed to some scientific points and facts regarding safety industry, impenetrability and consolidation of iron through putting a coating of copper on its sur...
متن کاملA review of Dolochar reuse methods (waste from sponge iron factories)
Background and Objective: Dolochar is the residual ash from the production of sponge iron in the process of direct reduction of iron ore by the coal-based method. In Iran, this waste is transported to the nearest landfill. However, these methods are a major environmental concern due to the fineness of the waste and the presence of heavy metals in its composition. The aim of the present study is...
متن کاملUsing Iron-Chelating Agents in Critically Ill Patients with Iron Overload. Fact or Fiction?
Recently, some evidence has shown that the failure of iron homeostasis may occur in critically ill patients and can lead to iron overload. Elevated ferritin levels as a body iron burden index in critically ill patients may be associated with depressed level of consciousness and greater mortality. However, the necessity of using iron-chelating agents in clinical situation is still unknown for th...
متن کامل